Intradialytic Neuromuscular Electrical Stimulation versus Cycling on Renin Hormone in Chronic Kidney Disease

Obaya, Hany Ezzat; Sedek, Ahmed Elsayed Eissa; Mohamed, Hassan Ismail; Draz, Ramy Salama

doi:10.21608/ermhs.2025.358106.1038

Intradialytic Neuromuscular Electrical Stimulation versus Cycling on Renin Hormone in Chronic Kidney Disease

Document Type : Original Article

Authors

¹ Department of Physical Therapy for Cardiovascular, Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University, Egypt.

² Department of Urology, Faculty of medicine, Al-Azhar University, Egypt.

10.21608/ermhs.2025.358106.1038

Abstract

Background: Worldwide accelerated advances in physical rehabilitation of chronic kidney disease; particularly whom undergoing haemodialysis. Multimodal therapeutic approaches may maximize their recovery through preliminary evidence indicating both intradialytic neuromuscular electrical stimulation or cycling exercise might permit obvious benefits.
Purpose: To investigate the effect of intradialytic neuromuscular electrical stimulation and cycling on renin hormone levels in patients with chronic kidney disease.
Material&Methods: A single prospective clinical, randomized control trial. Sixty participants of both genders with chronic kidney disease whom undergoing haemodialysis three times per week from ElQnatar Hospital, Qalyobia, Egypt. They were randomly allocated into two equal groups; Group A 30 subject received intradialytic neuromuscular electrical stimulation protocol; 3 session per week for eight weeks; and Group B 30 subject received intradialytic cycling exercise protocol for up to one hour per session; 3 session per week for eight weeks. Evaluation involving renin hormone test, leg musculature strength using dynamometer, kidney function test and frequency and number of sessions per month. Statistical analysis with significance level 0.05 level.
Results: Unsignificant differs revealed at baseline analysis. Both groups had revealed a significant decrease in renin hormone test reported values, and a significant increase in leg musculature strength, and kidney function test values, and frequency and number of sessions per month reported values post treatment. As well, there were significant improvement in group B compared with group A post treatment in term of renin hormone test values, leg musculatures` strength, frequency and number of sessions per month, as well kidney function test.

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